Drug Interactions With Almotriptan

Taking almotriptan with certain other medications -- such as other triptans, MAOIs, and some antidepressants -- can cause problems. Some of these almotriptan drug interactions can increase your risk of dangerous side effects or cause a group of symptoms called serotonin syndrome (which can include hallucinations, difficulty walking, and muscle spasms).

An Overview of Almotriptan Interactions

Almotriptan maleate (Axert®) can potentially interact with many other medicines. Some of the medicines that may lead to almotriptan interactions include:
 
 
 
 
 
 
 
   
  • Ergot medications, such as:
 
    • Bromocriptine (Parlodel®)
    • Dihydroergotamine (Migranal®)
    • Ergotamine (Bellamine S®, Cafergot®, Ergomar®)
    • Pergolide (Permax®)
 
  • Erythromycin (Ery-Tab®)
  • Itraconazole (Sporanox®)
  • Ketoconazole (Nizoral®)
  • Monoamine oxidase inhibitors (MAOIs), including:
 
    • Isocarboxazid (Marplan®)
    • Phenelzine (Nardil®)
    • Rasagiline (Azilect®)
    • Selegiline (Eldepryl®, Emsam®, Zelapar®)
    • Tranylcypromine (Parnate®)
 
 
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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