Butterbur

Butterbur is a type of plant that is supposedly beneficial for conditions such as allergies or migraines. This herbal supplement contains several active compounds that may have various medicinal properties. However, more research is necessary to confirm the effectiveness of this product for any use. Potential side effects include fatigue, headaches, and itchy eyes.

What Is Butterbur?

Butterbur is a daisy-like plant said to have medicinal properties. It is used for various conditions, such as allergies or migraines and is available in a variety of different dietary supplements.
 
(Click Butterbur Benefits for more information about possible uses for this product.)
 

How Does It Work?

Butterbur contains a variety of different active compounds, such as petasin, isopetasin, flavonoids, and tannins. It is thought that these compounds are probably responsible for most of the medicinal properties of the plant.
 
Butterbur is believed to relieve allergies by decreasing the production of leukotrienes and histamine, two substances in the body that are responsible for many of the symptoms of allergies. It is not yet clear how the supplement might work to prevent migraine headaches.
 

Is Butterbur Effective?

There is growing evidence to suggest that butterbur may actually work for preventing migraines or treating allergies. However, more research is necessary to confirm these findings and to explore the possibility that the supplement may be effective for other uses as well.
 
(Click Does Butterbur Work? for more information.)
 

Dosing Information

As with most dietary supplements, there is no well-established standard dose for butterbur, although general guidelines may be obtained from a few clinical trials (see Butterbur Dosage for more information).
 

Side Effects of Butterbur

Even though it is a "natural" product, butterbur can cause side effects. Some of the reported side effects include:
 
  • Itchy eyes
  • Headaches
  • Belching
  • Fatigue
  • Drowsiness.
     
(Click Butterbur Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 

Drug Interactions

Theoretically, butterbur may interact with some medications (see Butterbur Drug Interactions).
 

Safety Issues With Butterbur

Natural butterbur contains toxic alkaloids that can damage the liver and the lungs. Unless these alkaloids are removed (as is done with some high-quality supplements), this substance should not be considered safe. Some people may be more likely to experience problems with butterbur than others are. Therefore, you should talk with your healthcare provider prior to taking this product medicinally if you have:
 
  • Liver disease, such as liver failure, hepatitis, or cirrhosis
  • Any chronic or severe medical condition
  • Any allergies, including allergies to foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Is Butterbur Safe? for more information, including any available warnings and precautions.)
 

What If I Take an Overdose?

An overdose with this supplement could cause serious problems. If you think you or someone else may have taken too much butterbur, it is important to seek immediate medical attention.
 
(Click Butterbur Overdose for more information.)
 

Storage Methods for Butterbur

Refer to the label of your individual product for information on how best to store butterbur. Keep all medications and supplements out of the reach of children.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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