In one study, divalproex was added to other seizure medications in people with complex partial seizures that were not adequately controlled. Those who added it to their seizure medications decreased their seizure frequency, compared to those who did not take the drug.
Other studies have shown that using divalproex alone is also effective for complex partial seizures.
Some general considerations for when and how to take this medication include the following:
- Divalproex comes in delayed-release tablets and "sprinkle capsules."
- The medication can be taken with or without food. If divalproex upsets your stomach, try taking it with food.
- Do not crush, break, or chew the tablets, as this will destroy the protective coating.
- The sprinkle capsules can be swallowed whole or can be opened and the contents sprinkled on a spoonful of soft food (such as pudding or applesauce). Do not chew the contents, as each tiny bead is delayed-release, with a special protective coating.
- Divalproex should be taken at the same times each day to maintain an even level in your blood.
- For the medication to work properly, it must be taken as prescribed. Divalproex will not work if you stop taking it.
- Do not stop taking the medication without first discussing it with your healthcare provider (see Depakote Withdrawal).
The dose of divalproex your healthcare provider recommends will vary, depending on a number of factors, including:
- The medical condition being treated
- Your weight
- Other medications you may be taking
- Other medical conditions you may have.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Divalproex Dosing for more information.)