Imitrex Drug Interactions

Imitrex Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Imitrex is combined with any of the drugs listed above.
Certain Antidepressants
Taking Imitrex with certain depression medications can cause a group of symptoms called serotonin syndrome. These symptoms include:
  • Confusion
  • Hallucination
  • Fast heartbeat
  • Feeling faint
  • Fever
  • Sweating
  • Muscle spasm
  • Difficulty walking
  • Diarrhea.
Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be very dangerous.
There are special warnings for MAOIs. Taking Imitrex with a type A MAOI can greatly increase the amount of Imitrex in your blood, increasing your chance of dangerous Imitrex side effects. Do not take Imitrex if you have used a type A MAOI within the last two weeks. Although selegiline and rasagiline are usually considered to be type B MAOIs, they may also be MAO-A inhibitors when used at high doses. Ask your healthcare provider before taking Imitrex with selegiline or rasagiline.
Ergot Medications
Taking Imitrex with ergot medications can increase your risk of dangerous side effects. Do not take Imitrex and ergot medications within 24 hours of each other.
Taking Imitrex with other triptans can increase your risk of serious side effects. These medications should not be taken within 24 hours of each other.

Imitrex Drug Interactions: Summary

It is possible that not every drug interaction with Imitrex was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about specific Imitrex drug interactions that may apply to you.
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Imitrex Info

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