Among the drugs that can potentially interact with Imitrex are ergot medications, monoamine oxidase inhibitors (MAOIs), and certain antidepressants. Imitrex drug interactions can increase the level of Imitrex in your blood or your risk of dangerous side effects, among other things. Also, taking Imitrex along with certain antidepressants can cause a group of symptoms called serotonin syndrome. Some of these symptoms include hallucinations, sweating, difficulty walking, and a fever.
