Imitrex for Migraines (Cont.)

How Does Imitrex Work to Treat Migraines?

Imitrex is part of a class of migraine medications called 5-HT agonists (or more commonly known as "triptans"). During a migraine headache, some of the blood vessels in the head can become dilated (wider than they usually are). Imitrex works by narrowing these blood vessels, helping them return to their normal state. This action helps to relieve migraine symptoms.
 
Imitrex should be taken as soon as possible once a migraine starts. If your headache comes back or does not go away, you may take a second dose of Imitrex after waiting at least two hours from the time you took the first dose of Imitrex tablets or Imitrex nasal spray (or one hour after the first dose of an Imitrex injection). Let your healthcare provider know if Imitrex does not work completely after one dose.
 

Imitrex Effects on Migraine Pain

In one study, 52 to 62 percent of people with migraines had no (or mild) pain within two hours of taking Imitrex tablets, compared to only 27 percent who did not take Imitrex. Within four hours, as many as 79 percent of people who had taken Imitrex had migraine relief, compared to just 38 percent of people not taking Imitrex. Similar results were seen in studies of Imitrex nasal spray and Imitrex injection.
 

Final Thoughts on Imitrex for Migraines

Imitrex is a prescription medicine used for treating migraines. It does not prevent migraines from occurring (see Migraine Prevention). Although the drug is quite effective in treating migraine headaches, it is not right for everyone (see Imitrex Warnings and Precautions). It can also cause side effects in some people, such as tingling, dizziness, and chest discomfort.
 
(Click Imitrex Alternatives to read about other migraine medications.)
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;