Headache Home > Axert and Pregnancy

The FDA has classified Axert as a pregnancy Category C medication, meaning that it did appear to cause harm to the fetus in previous animal studies. When Axert was given to pregnant rats during pregnancy and breastfeeding, the number of embryo deaths increased and the baby rats weighed less and suffered from bone changes. If you are pregnant or thinking of becoming pregnant, you should be sure to talk to your healthcare provider about Axert and pregnancy. He or she may still prescribe Axert if the benefits outweigh the risks.

An Overview of Axert and Pregnancy

For women who are pregnant, Axert® (almotriptan maleate) may not be safe. This is based on animal studies that looked at the effects of Axert during pregnancy.
 

Axert and Pregnancy Category C

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans, but do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
 
Axert was given a pregnancy Category C rating based on studies in pregnant animals. For example, when Axert was given to pregnant rats during pregnancy and breastfeeding, the number of embryo deaths increased and the baby rats weighed less. Also, Axert caused bone changes in the baby rats.
 
It is important to note that animals do not always respond to medicines in the same way that humans do. Therefore, a pregnancy Category C medicine may be given to a pregnant woman if her healthcare provider believes that its benefits outweigh any possible risks to her unborn child.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation
Advertisement


Topics

Medications

Quicklinks

Related Channels

eMedTV Links
Copyright © 2006-2018 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.