Affecting an estimated 28 million Americans, migraine headaches are characterized by severe pain that is felt mostly in the front, around the temples, or behind one eye or ear. The pain can last a few hours or up to one or two days. The exact causes of migraines are unknown, but some common triggers include lack of sleep, stress, and certain foods. Migraines most often affect people between the ages of 15 and 55. Treatment options for a migraine can include medications, lifestyle changes, and alternative therapies, such as acupuncture.