Sumavel Warnings and Precautions

Specific Precautions and Warnings With Sumavel

Some warnings and precautions to be aware of prior to taking Sumavel include the following:
  • In rare cases, serious problems such as heart attacks or life-threatening changes in heart rhythm (arrhythmias) have been reported with Sumavel or other forms of sumatriptan. You should not take this drug if you have heart disease or a history of heart attack or chest pain (see Sumavel and Heart Problems for more information).
If you have risk factors for heart disease (see Heart Disease Risk Factors), it is strongly recommended that you take your first Sumavel dosage in your healthcare provider's office so that he or she can monitor your heart. You should also have your heart checked periodically during treatment.
  • In some cases, a stroke or transient ischemic attack ("mini-stroke") can be misdiagnosed as a migraine. Your healthcare provider should make sure you are not having a stroke, especially if you have never had migraines before (see Stroke Symptoms for more information).
  • If you have chest pain or jaw or neck tightness after taking Sumavel, contact your healthcare provider immediately. These side effects are fairly common with this drug and are not usually serious. However, your healthcare provider may need to make sure you are not having heart problems.
  • Medications like Sumavel can cause blood vessels to spasm, including in the arms, legs, or colon (large intestine). This can cause a decrease in blood flow to these areas. Symptoms will vary based on the location. For example, a spasm in the colon can lead to severe abdominal (stomach) pain or bloody diarrhea.
  • Taking Sumavel with certain antidepressants, including selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs), can increase your risk of a dangerous group of symptoms called serotonin syndrome. Do not use Sumavel with depression medications without first discussing it with your healthcare provider. Contact your healthcare provider immediately if you have any possible symptoms of serotonin syndrome, including:
    • Confusion
    • Seeing or hearing things that are not really there (hallucinations)
    • Fast heartbeat (tachycardia)
    • Feeling faint
    • Fever
    • Sweating
    • Muscle spasms
    • Difficulty walking
    • Diarrhea.
  • This medication can cause an increase in blood pressure. You should not take it if you have untreated high blood pressure (hypertension).
  • Sumavel is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy. Talk to your healthcare provider before using this drug if you are pregnant (see Sumavel and Pregnancy for more information).
  • This medicine passes through breast milk. Therefore, if you are breastfeeding or plan to start, talk with your healthcare provider before beginning treatment (see Sumavel and Breastfeeding).
  • There have been rare reports of seizures associated with the use of Sumavel or other forms of sumatriptan. People with a history of seizures or epilepsy should use this medication with caution.
  • Sumavel can interact with certain medications (see Sumavel Drug Interactions).
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