Treximet and Dry Mouth

As with any medication, it is possible to develop side effects while taking Treximet (sumatriptan/naproxen sodium). Dry mouth is a potential side effect that has been reported in up to 2 percent of people taking the medication during clinical trials. If you are taking Treximet and dry mouth becomes a problem, you can try sipping water more often, avoiding tobacco, or contacting your healthcare provider for more suggestions.

 

Does Treximet Cause a Dry Mouth?

Treximet™ (sumatriptan/naproxen sodium) is a prescription migraine medication. Dry mouth is one of the possible Treximet side effects. In clinical studies, up to 2 percent of people taking Treximet reported having a dry mouth, compared to only 1 percent of people who took a placebo (a "sugar pill" with no active ingredients).
 

Treximet and Dry Mouth: Suggestions

A dry mouth due to Treximet (or any other medication) need not be something you must simply suffer through. There are several tips and tricks that can help alleviate a dry mouth, such as:
 
  • Chew sugarless gum or suck on sugarless hard candy to stimulate saliva flow; cinnamon- or mint-flavored candies are good choices.
     
  • Sip water or sugarless drinks often.
     
  • Sip water or sugarless drinks during meals. This will make chewing and swallowing easier; it may also improve the taste of food.
     
  • Avoid drinks with caffeine, such as coffee, tea, and some sodas. Caffeine can dry out the mouth.
     
  • Don't use tobacco or alcohol, because they dry out the mouth.
     
  • Use a humidifier at night.
     
  • Be aware of spicy or salty foods, since they can cause pain in a dry mouth.
     
Typically, a dry mouth is simply bothersome. However, a severely dry mouth (over a long period of time) can lead to serious dental problems. If your dry mouth is very severe or is not helped by any of these suggestions, please let your healthcare provider know.
 
(Treximet and Dry Mouth Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;