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Treximet Warnings and Precautions
It is important to talk to your healthcare provider about Treximet warnings and precautions, as it is possible to develop side effects or complications while taking the medication. Treximet could increase the risk of heart attacks or strokes, bleeding, and seizures. You should avoid taking Treximet if you have untreated high blood pressure, liver problems, or a history of angina.
You should talk with your healthcare provider prior to using Treximet™ (sumatriptan/naproxen sodium) if you have:
- Heart problems of any kind, especially a history of heart disease, angina, an irregular heart rhythm, or a heart attack
- A history of stroke, transient ischemic attack (TIA or "mini-stroke"), or other bleeding in the brain (such as a subarachnoid hemorrhage)
- Congestive heart failure (CHF)
- High blood pressure (hypertension)
- High cholesterol
- Diabetes
- Certain blood vessel conditions, such as peripheral vascular disease, ischemic bowel disease, or Raynaud's phenomenon
- Kidney problems, including kidney failure (renal failure)
- Liver problems, including liver failure or cirrhosis
- A history of seizures or epilepsy
- Asthma
- Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you:
- Are pregnant or thinking of becoming pregnant
- Are breastfeeding
- Smoke
- Have a family history of heart disease.
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD