Taking Zomig with cimetidine can raise the amount of Zomig in your blood, increasing your risk of side effects. If you are taking these drugs together, your healthcare provider may need to decrease your dose of Zomig or may recommend a cimetidine alternative.

 

Taking Zomig with certain depression medications, including selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), can cause a group of symptoms called serotonin syndrome. These symptoms may include confusion, hallucinations, a fast heartbeat, feeling faint, a fever, sweating, muscle spasms, difficulty walking, and diarrhea. Talk with your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be very dangerous.

 

Taking Zomig with ergot medications can increase your risk of dangerous side effects. Do not take Zomig and ergot medications within 24 hours of each other.

 

Taking Zomig with type A monoamine oxidase inhibitors can increase the amount of Zomig in your blood, perhaps increasing your chance of side effects. Do not take Zomig if you have used an MAO-A inhibitor within the last two weeks.

 

In previous studies, selegiline (a type B monoamine oxidase inhibitor) did not have any effect when taken with Zomig. However, at higher doses selegiline is also a type A monoamine oxidase inhibitor. Therefore, talk with your healthcare provider before taking selegiline and Zomig together.

 

Taking Zomig with other triptans can increase your risk of serious side effects. These medications should not be taken within 24 hours of each other.